ODCs

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1 OMIM reference -
1 associated gene
10 signs/symptoms

PROTEIN INTERACTIONS: 3
COMMON SIGNS: 1

1 OMIM reference -
5 associated genes
13 signs/symptoms

Papilloma of choroid plexus

Multiple endocrine neoplasia type 1


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	TP53 TP53 TP53	(0.88) (0.73) (0.56)	CDKN1A CDKN2C MEN1

Citations in the biomedical literature:

Papilloma of choroid plexus		Multiple endocrine neoplasia type 1
	Synonym(s): (no synonyms)		Synonym(s): - MEN 1 - Wermer syndrome

	Classification (Orphanet): - Rare neurologic disease - Rare oncologic disease		Classification (Orphanet): - Rare endocrine disease - Rare gastroenterologic disease - Rare genetic disease - Rare oncologic disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Neoplasms -

	Epidemiological data: (no data available)		Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: variable Average age of death: adult Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - 1 MeSH reference: D020288		External references: 1 OMIM reference - 1 MeSH reference: D018761

Papilloma of choroid plexus		Multiple endocrine neoplasia type 1
	Very frequent - Autosomal recessive inheritance - Central nervous system / peripheral nerves neoplasm / tumor / carcinoma / cancer - Hydrocephaly - Structural anomalies of the nervous system Occasional - Hemiplegia / diplegia / hemiparesia / limb palsy - Hypertonia / spasticity / rigidity / stiffness - Intellectual deficit / mental / psychomotor retardation / learning disability - Mild visual loss / impaired visual acuity - Seizures / epilepsy / absences / spasms / status epilepticus		Very frequent - Anomalies of the endocrine glands - Anomaly of pancreatic hormones - Autosomal dominant inheritance - Hypercalcemia - Hyperparathyroidy - Hypothalamic-hypophyseal axis anomalies / hypothalamus / pituitary anomalies - Parathyroids anomalies - Structural anomalies of the pancreas Frequent - Cortico-adrenal hyperplasia / hypersecretion - Epigastralgia / heartburn / gastric / duodenal ulcer / gastritis - Thyroid anomalies - Xanthomas / lipomas